Though there are a number causes of weight loss but the following are the main ones which a physician tends to look for particularly in the history and physical examination. In clinical setting and medical exams alike, these cardinal signs should not be missed by a physician.Significant weight loss is a loss of 4.5 kg or > 5% body weight over 6 – 12 months according to the NCBI. Any person presenting with weight-loss should be investigated and worked up for the following causes.
  • CAUSES OF WEIGHT LOSSMALABSORPTION
Loss of appetite
Bloating and difficulties in wind passage Stool which difficult to flush
Manifestation of vitamin deficiency

 

CAUSES OF WEIGHT LOSS
  •  INFECTIONS
  • Tuberculosis
  • AIDS
  • History of sexual contact , travel abroad and blood products transfusion should be inquired.

 

  •  Signs and symptoms of Diabetes (Polyuria, polydipsia, polyphagia) and Thyrotoxicosis (unexplained diarrhea, profuse sweating, tachycardia, tremors, hypertension) should also be look for.
CAUSES OF WEIGHT LOSS
  •  MALIGNANCY
Any swelling such as lymph node enlargement  or lumps or pyrexia of unknown origin can be the presenting symptom
  • GASTROINTESTINAL CAUSES
  • CROHN’S DISEASE
  • PARASITIC INFESTATION
  • PEPTIC ULCER DISEASE

 

  • Psychiatric illness particularly Depression associated with a loss of near / dear one or financial loss can also lead to a weight loss.